O Movimento do Microbioma
publicado em 11/04/2020
Travis Whitfi ll
Azitra Inc., Farmington, CT, e Faculdade de Medicina da Universidade de Yale, New Haven, CT, EUA
Vários fatores determinam a forma do microbioma cutâneo de um indivíduo, com efeitos importantes na aparência e na saúde da pele. Este artigo descreve esses fatores, além das possibilidades para o desenvolvimento de produtos cosméticos, considerando o tipo do microbioma.
Various factors shape an individual´s skin microbiome, which has key effects on skin appearance and health. These are described herein, as is the potential to develop products in consideration of the microbiome.
Varios factores determinan la forma del microbioma cutáneo de un individuo, com efectos importantes en la apariencia y la salud de la piel. Este artículo describe estos factores, además de las posibilidades para el desarrollo de productos cosméticos, considerando el tipo del microbioma.
Rupturas no Microbioma da Pele
Os Cosméticos e o Microbioma da Pele
Considerações Sobre Produtos Tópicos
A pele humana tem função de barreira em relação ao mundo externo e é rica em microrganismos que desempenham papel fundamental na manutenção da saúde humana.1-7 O microbioma da pele – a maior parte adquirida no nascimento8 – é formado por diversas comunidades de microrganismos que habitam a pele. Um centímetro quadrado de pele pode conter até 1 bilhão de microrganismos (Figura 1).9 Essas diferentes comunidades de bactérias, fungos, ácaros e vírus podem proporcionar proteção contra doenças e formam nichos dinâmicos e diferenciados na pele.10 Frequentemente, as bactérias são consideradas o grupo de microrganismos mais abundante no ecossistema da pele, sendo encontradas desde na parte interna das camadas superiores da pele até a camada dérmica inferior.
O microbioma da pele é altamente diversificado, havendo significante grau de variação “intraindividual”. Na pele de um mesmo indivíduo, existem vários microambientes simultaneamente, conforme temperatura, umidade, pH, conteúdo de sebo, exposição à radiação UV etc., fatores que geram diferenças entre as populações de micróbios.6
Com base nessas condições, o microbioma da pele pode ser essencialmente classificado de acordo com o tipo de pele: gordurosa (por exemplo, na testa e na
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