Fotoenvelhecimento e Recuperação da Pele
publicado em 01/10/2007
Martin Rieger, PhD
Tinton Falls, NJ, Estados Unidos
Esta revisão periódica é uma tentativa de alertar os leitores sobre as mais recentes tendências na pesquisa da pele. Os assuntos foram organizados nos seguintes termos: impacto da luz sobre a pele humana normal, fotoenvelhecimento e recuperação da pele, com destaque especial para a recuperação da pele fotoenvelhecida induzida por medicamentos.
This periodical review is an effort to make readers aware of recent trends in skin research. The subjects have been organized into the impact of light on human skin, photo-aging and skin repair, with special emphasis on the drug-induced repair of photo-aged skin.
Esta revisión periódica es una tentativa de alertar a los lectores sobre las más recientes tendencias en la pesquisa de la piel. Los asuntos fueran organizados en términos del impacto de la luz sobre la piel humana normal, fotoenvejecimiento y recuperación de la piel, com énfasis especial en la reparación inducida por medicamentos de la piel de foto-envejecida.
Fotoestabilidade
Biologia da Pele
Peptídeos Antimicrobianos
Reações Adversas e Doenças de Pele
Penetração na Pele
Fenômenos e Técnicas da Pele
Olhada nos Cabelos
Relatórios de pesquisas de dermatologistas continuam a apontar para a necessidade de fotoproteção e, mais recentemente, para a recuperação do fotoenvelhecimento.
Independente da origem dos relatórios, os objetivos das investigações são visivelmente semelhantes. Contribuições típicas documentam que as irradiações UVA e UVB induzem respostas semelhantes das células da pele humana.3 Porém, há apenas alguns meses, uma carta para a mesma publicação afirma que a ubiquinona, idebenona e quinetina protegem a pele menos efetivamente do que uma combinação de antioxidante tópico de ácido ascórbico, vitamina E e ácido ferúlico.2 Substâncias de oxigênio reativo se formam durante a existência aeróbia no ambiente. Isso foi considerado, por muitos anos, potencialmente perigoso, e o peróxido de hidrogênio continua sendo uma das mais perigosas substâncias formadas durante a fotoexposição.3,4
As características de destaque do fotoenvelhecimento são as alterações da derme, em suas fibras elásticas e microvascularização, e da epiderme, nos queratinócitos, células de Langerhans e melanócitos. Por outro lado, a pele fotoenvelhecida nunca foi minuciosamente estudada.
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